Spotlight Publications

These publications represent contributions that helped advance understanding in frailty, mitochondrial biology, and technology-enabled aging research.

1. Metabolomics-based Identification of Metabolic Dysfunction in Frailty
Westbrook R, Zhang C, Yang H, et al. J Gerontol A Biol Sci Med Sci. 2021.
Link to article
→ Impact: Defined metabolic signatures of frailty; guided biomarker discovery.

2. Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes
Abadir PM, et al. Circulation. 2017.
Link to article
→ Impact: Identified novel prognostic biomarkers with clinical implications for aging.

3. Kynurenines Link Chronic Inflammation to Functional Decline and Physical Frailty
Westbrook R, Chung T, Walston JD, Abadir PM*. JCI Insight. 2020.
Link to article
→ Impact: Connected immune pathways to physical frailty via tryptophan metabolism.

4. Artificial Intelligence and Technology Collaboratories: Innovating Aging Research and Alzheimer’s Care
Abadir P*, Oh ES, Chellappa R, et al. Alzheimers Dement. 2024.
Link to article
→ Impact: Outlined a national AI strategy for aging and dementia research.

5. Dual Treatment with Kynurenine Pathway Inhibitors and NAD+ Precursors Synergistically Extends Lifespan in Drosophila
Gabrawy MM, Westbrook R, Abadir PM*. Aging Cell. 2024.
Link to article
→ Impact: Identified promising combination therapy to delay biological aging.

Thematic Areas

Frailty & Molecular Biology

AI & Aging Technologies

Translational Wound Healing

Editorials and Thought Leadership

The Promise of AI and Technology to Improve Quality of Life for Older Adults
Abadir PM*, et al. Nat Aging. 2023.
Read the article

Artificial Intelligence in Geriatrics: Riding the Tide
Abadir P*, Chellappa R. J Gerontol A. 2024.
Read the editorial