THE ABADIR LAB · JOHNS HOPKINS
Connecting molecular aging biology with medicine, engineering, and AI to advance health and independence.
MITOCHONDRIA · RAS · INFLAMMATIONExplore the molecular foundations ↗
A QUESTION THAT CONNECTS OUR WORK
The answer begins in our cells. It also lives in how we move, recover, think, and engage with the world.
At the Abadir Lab, we study frailty and resilience across these scales. We investigate mitochondrial signaling, inflammation, and metabolism, then connect that biology with clinical measurements and emerging technologies.
Our work brings laboratory discovery into conversation with the everyday needs of older adults.
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THE MOLECULAR FOUNDATION
Our research into the renin–angiotensin system (RAS) and mitochondrial function connects cellular mechanisms with vascular aging, frailty, and resilience.
THE WEEKLY COLUMN
A closer look at AI, molecular biology, and the research shaping later life.
All editionsA better aging score, a clearer molecular mechanism, a stronger handgrip: each can move the field forward. This week’s research asks us to be precise about which step we have actually taken—and what would bring it closer to daily life.
CONNECTED RESEARCH
Explore the work at the heart of the lab.
Mitochondria, angiotensin signaling, and inflammatory pathways.
Molecular markers, metabolism, and physical and cognitive function.
Targeted drug delivery, tissue repair, and clinical investigation.
GERIATRICS + ENGINEERING
A place where clinical needs shape the next technology.
At Johns Hopkins, Geriatrics Engineering creates space for clinicians and engineers to work side by side. The Bayview hub connects laboratories, a model apartment, and technologies for studying everyday function.
PHYSICIAN. SCIENTIST. MENTOR.
Professor of Medicine · Johns Hopkins University
Connecting scientific discovery with the people it is meant to serve.
A geriatrician and translational researcher, Dr. Abadir brings together molecular aging science, clinical investigation, and engineering. His work spans the laboratory, interdisciplinary research programs, mentorship, and patient care.
Biography, leadership & mentorshipDISCOVERY IN PRINT
Journal of the American Geriatrics Society
A multidisciplinary discussion of the opportunities and practical challenges of AI in care for older adults.
Journal of Clinical Investigation
A review of RAS biology and its relevance to aging and translational research.
The Journals of Gerontology: Series A
Examining associations between tissue-derived DNA fragments, frailty, and cardiovascular outcomes.
TRAINING & MENTORSHIP
Research training connects molecular science, clinical investigation, and engineering. Through the Translational Aging Research T32, K24-supported mentorship, and GeroTech, trainees develop skills across disciplines.
Explore training pathwaysUNDERSTANDING FRAILTY
Explore our guide to frailty, biological reserve, and the ability to recover from stress.
Explore the guide & videosFOLLOW THE FIELD
Recent research, news, and trial updates across the areas that connect our work.
Explore all updatesArtificial intelligence, digital biomarkers, and technologies for older adults.
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Mitochondria, cellular signaling, inflammation, and the biology of aging.
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Clinical trials and interventions supporting function and independence in older adults.
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IN FOCUS
GERIATRICS ENGINEERING · NOVEMBER 2025
The launch of the Bayview hub brings clinical and engineering teams together.
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AI & AGING · 2026
A multidisciplinary special article considers AI and health care for older adults.
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LAB LIFE & COLLABORATION
Moments from laboratory work, shared spaces, research demonstrations, and events.
Explore the photographsRESEARCH. TRAINING. COLLABORATION.